文献类型：期刊文献

英文题名：A calorimetric and turn-on NIR fluorescent probe based on xanthene system for sensitive detection of thiophenol and its application in bioimaging

作者：Guo, Shao-Hua[1,2];Leng, Tao-Hua[3];Wang, Kai[1,2];Wang, Cheng-Yun[1,2];Shen, Yong-Jia[1,2];Zhu, Wei-Hong[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Shanghai Inst Qual Inspect & Tech Res, Natl Food Qual Supervis & Inspect Ctr Shanghai, Shanghai 200233, Peoples R China

年份：2018

卷号：185

起止页码：359

外文期刊名：TALANTA

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000433656200048)】；

基金：The authors are grateful to financial support from National Key Program of China (No.2016YFA0200302), Natural Science Foundation of Shanghai (No. 16ZR1408000) and the Fundamental Research Funds for Central Universities.

语种：英文

外文关键词：Near-Infrared (NIR) fluorescence; Probe; Thiophenol; Bioimaging

摘要：Developing fluorescent probes for specific detection of extremely toxic thiophenols is pretty significant in the field of environment, chemistry and biology. We report herein a turn-on red fluorescent xanthene-based probe (RD-Probe) for detecting thiophenol with high selectivity over other analytes including aliphatic thiols. The probe could play the part of a "naked-eye"colorimetric indicator toward thiophenol. Moreover, the relative fluorescence intensity at 653 nm displayed good linearity with the concentration of thiophenol ranging from 0 to 6 mu M, and the limit of detection for thiophenol could be as low as 15 nM. Furthermore, the practicability of RD-Probe has been successfully proved through the quantitative thiophenol detection in real water samples and fluorescence bioimaging of thiophenol in HeLa cells.