文献类型：期刊文献

中文题名：Fluorescent probes and functional materials for biomedical applications

作者：Xi-Le Hu[1];Hui-Qi Gan[1];Fan-De Meng[1];Hai-Hao Han[1];De-Tai Shi[5];Shu Zhang[3];Lei Zou[1];Xiao-Peng He[1];Tony D.James[2,4]

机构：[1]Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering,Feringa Nobel Prize Scientist Joint Research Center,School of Chemistry and Molecular Engineering,East China University of Science and Technology,Shanghai 200237,China;[2]Department of Chemistry,University of Bath,Bath BA27AY,UK;[3]Liver Cancer Institute,Zhongshan Hospital,and Key Laboratory of Carcinogenesis and Cancer Invasion(Ministry of Education),Fudan University,Shanghai 200032,China;[4]School of Chemistry and Chemical Engineering,Henan Normal University,Xinxiang 453007,China;[5]School of Materials Science and Engineering,Jingdezhen Ceramic Institute,Jingdezhen 333403,China

年份：2022

卷号：16

期号：10

起止页码：1425

中文期刊名：Frontiers of Chemical Science and Engineering

外文期刊名：化学科学与工程前沿（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2021_2022】；PubMed;

基金：the National Natural Science Foundation of China(Grant Nos.21907030 and 22108077);the International Cooperation Program of Shanghai Science and Technology Committee(Grant No.19410712600);De-Tai Shi would like to thank the Natural Science Foundation of Jiangxi(Grant No.20161BAB213067);the Scientific Research Fund of Jiangxi Provincial Education Department(Grant No.GJJ170807);Tony D.James wishes to thank the Royal Society for a Wolfson Research Merit Award;the Open Research Fund of the School of Chemistry;Chemical Engineering,Henan Normal University for support(Grant No.2020ZD01).

语种：英文

中文关键词：fluorescent probes;imaging;cell;biomedicine;biomolecules

摘要：Due to their simplicity in preparation,sensitivity and selectivity,fluorescent probes have become the analytical tool of choice in a wide range of research and industrial fields,facilitating the rapid detection of chemical substances of interest as well as the study of important physiological and pathological processes at the cellular level.In addition,many long-wavelength fluorescent probes developed have also proven applicable for in vivo biomedical applications including fluorescenceguided disease diagnosis and theranostics(e.g.,fluorogenic prodrugs).Impressive progresses have been made in the development of sensing agents and materials for the detection of ions,organic small molecules,and biomacromolecules including enzymes,DNAs/RNAs,lipids,and carbohydrates that play crucial roles in biological and disease-relevant events.Here,we highlight examples of fluorescent probes and functional materials for biological applications selected from the special issues“Fluorescent Probes”and“Molecular Sensors and Logic Gates”recently published in this journal,offering insights into the future development of powerful fluorescence-based chemical tools for basic biological studies and clinical translation.