文献类型：期刊文献

英文题名：Pd-catalyzed diastereoselective 1,1-diarylation of 1,1-disubstituted alkenes enabling the modular synthesis of 1,1,2,2-tetraarylethanes

作者：Zhang, Chengxi[1];Xi, Yang[1];Qu, Jingping[1];Chen, Yifeng[1]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat & Joint Int Res Lab Precis Chem &, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Mat & Dynam Chem,School Chem &, Shanghai 200237, Peoples R China

年份：2023

卷号：66

期号：12

起止页码：3539

外文期刊名：SCIENCE CHINA-CHEMISTRY

收录：;EI(收录号：20234715088866);WOS:【SCI-EXPANDED(收录号:WOS:001110878900018)，CCR-EXPANDED(收录号:WOS:001110878900018)】；

语种：英文

外文关键词：1, 1, 2, 2-tetraarylethane; palladium; cross-coupling reaction; alkene; multicomponent reactions

摘要：The highly diastereoselective dicarbofunctionalization of substituted olefins still remains a daunting challenge in synthetic chemistry. Herein, we report a Pd-catalyzed diastereoselective 1,1-diarylation of 1,1-diarylethylene with chelation group free to enable the modular synthesis of smart material candidates, 1,1,2,2-tetraarylethanes (TAEs), which represent the first protocol by assembling four different aryl groups into ethane motif. Preliminary mechanistic experiments suggest that the crucial Pd-H species generated in situ do not disengage from the alkene intermediate during the reaction.