文献类型：期刊文献

英文题名：Simple and Cost-Effective Glucose Detection Based on Carbon Nanodots Supported on Silver Nanoparticles

作者：Ma, Jin-Liang[1];Yin, Bin-Cheng[1];Wu, Xin[3];Ye, Bang-Ce[1,2]

机构：[1]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Lab Biosyst & Microanal, Shanghai 200237, Peoples R China;[2]Shihezi Univ, Sch Chem & Chem Engn, Xinjiang 832000, Peoples R China;[3]Second Mil Med Univ, Shanghai Changzheng Hosp, Dept Rheumatol & Immunol, Shanghai 200433, Peoples R China

年份：2017

卷号：89

期号：2

起止页码：1323

外文期刊名：ANALYTICAL CHEMISTRY

收录：;EI(收录号：20174804480937);WOS:【SCI-EXPANDED(收录号:WOS:000392458100041)】；

基金：This work was jointly supported by the National Natural Science Foundation of China (Grants 21335003, 21675052, 21575089), the Fundamental Research Funds for the Central Universities, the Science Fund for Creative Research Groups (Grant 21421004), and Programme of Introducing Talents of Discipline to Universities (Grant B16017).

语种：英文

外文关键词：Metal ions - Chemical modification - Metal nanoparticles - Fluorescence quenching - Nanodots - Cost effectiveness - Silver nanoparticles - Energy transfer - Glucose oxidase - Glucose sensors

摘要：We present a new glucose oxidase (GOx)-mediated strategy for detecting glucose based on carbon nanodots supported on silver nanoparticles (C-dots/AgNPs) as nanocomplexes. The strategy involves three processes: quenching of C-dots fluorescence by AgNPs, production of H2O2 from GOx-catalyzed oxidation of glucose, and H2O2-induced etching of AgNPs. In the C-dots/AgNPs complex, AgNPs act as a nanoquencher to decrease C-dots fluorescence by surface plasmon-enhanced energy transfer (SPEET) from C-dots (donor) to AgNPs (acceptor). The H2O2 formed by GOx-catalyzed oxidation of glucose etches the AgNPs to silver ions, thus freeing the C-dots from the AgNPs surfaces and restoring the C-dots fluorescence. Therefore, the increase in fluorescence depends directly on the concentration of H2O2, which, in turn, depends on the concentration of glucose. The strategy allows the quantitative analysis of glucose with a detection limit of 1.39 mu M. The method based on C-dots/AgNPs offers the following advantages: simplicity of design and facile preparation of nanomaterials, as well as low experimental cost, because chemical modification and separation procedures are not needed.