文献类型：期刊文献

英文题名：Synthesis of Oxazolidin-2-ones via a Copper(I)-Catalyzed Tandem Decarboxylative/Carboxylative Cyclization of a Propiolic Acid, a Primary Amine and an Aldehyde

作者：Feng, Huangdi[1,2];Ermolat'ev, Denis S.[1];Song, Gonghua[2];Van der Eycken, Erik V.[1]

机构：[1]Katholieke Univ Leuven, LOMAC, Dept Chem, Celestijnenlaan 200F, B-3001 Louvain, Belgium;[2]E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2012

卷号：354

期号：2-3

起止页码：505

外文期刊名：ADVANCED SYNTHESIS & CATALYSIS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000300448400032)，CCR-EXPANDED(收录号:WOS:000300448400032)】；

基金：The authors wish to thank the F.W.O. [Fund for Scientific Research - Flanders (Belgium)] and the Research Fund of the Katholieke Universiteit Leuven for financial support to the laboratory. D.S.E. is grateful to the F.W.O. for providing a postdoc fellowship. H. D. F. thanks the China Scholarship Council for financial support.

语种：英文

外文关键词：carboxylative cyclization; decarboxylative coupling; oxazolidinones; three-component coupling

摘要：A facile approach to polysubstituted oxazolidin-2-ones is presented via a copper(I)-catalyzed tandem decarboxylative/carboxylative cyclization of a propiolic acid, a primary amine and an aldehyde (PA2-coulpling). This new multicomponent coupling constitutes an efficient methodology to provide the corresponding oxazolidin-2-ones in good yields.