文献类型：期刊文献

英文题名：Direct Access to Acylated Azobenzenes and Amide Compounds by Reaction of Azoarenes with Benzylic Ethers as Acyl Equivalents

作者：Hong, Gang[1,2];Aruma, Alfred Njasotapher[1,2];Zhu, Xiaoyan[1,2];Wu, Shengying[1,2];Wang, Limin[1,2,3]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China

年份：2016

卷号：48

期号：8

起止页码：1147

外文期刊名：SYNTHESIS-STUTTGART

收录：;EI(收录号：20160902002009);WOS:【SCI-EXPANDED(收录号:WOS:000373689600008)，CCR-EXPANDED(收录号:WOS:000373689600008)】；

基金：This research was financially supported by the National Nature Science Foundation of China (21272069, 20672035) and the Fundamental Research Funds for the Central Universities and Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.

语种：英文

外文关键词：azobenzenes; synthetic methods; radical reaction; directing group; benzylic ether; amide compounds

摘要：Described herein is the use of N=N double bond of azobenzene as both directing group and radical acceptor in one-reaction protocol for the first time. An efficient pathway for the Pd-catalyzed regio-specific ortho-acylation of azoarenes using benzylic ethers as acyl equivalents has been achieved. In the absence of palladium catalyst, amide compounds were formed by the reaction of azoarenes with benzylic ethers under certain conditions. Various mono-acylazobenzene and amide compounds were obtained in good yields (35 examples). The mono-acylated products and amide products could be easily controlled by palladium catalyst.