文献类型：期刊文献

英文题名：Polyhedral Oligomeric Silsesquioxanes (Poss) Bioconjugates

作者：Zhang, Weian[1]; Zhang, Zhenghe[1]; Hong, Lizhi[1]

机构：[1] Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, Shanghai, China

年份：2014

卷号：9781118359143

起止页码：344

外文期刊名：Chemistry of Bioconjugates: Synthesis, Characterization, and Biomedical Applications

收录：EI(收录号：20182705492803)

语种：英文

外文关键词：Biomolecules - Controlled drug delivery - Medical imaging - Molecules - Peptides - Scaffolds - Scaffolds (biology) - Targeted drug delivery - Tissue

摘要：In the last two decades, polyhedral oligomeric silsesquioxane (POSS) has attracted considerable attention. POSS molecules can be modified into a variety of POSS derivatives based on their corner groups. POSS molecule has been considered to be the promising material in biological fields, according to the unique structure and properties of POSS derivatives. This chapter gives some examples to describe the construction and properties of POSS-containing bioconjugates based on peptides/proteins, carbohydrates, and DNA, and highlights their potential applications as biomedical devices, tissue engineering materials, dental materials, drug delivery, and biological images. The preparation and application of well-defined POSS-containing bioconjugates with other architectures needs to be explored in the future. ? 2014 by John Wiley & Sons, Inc. All rights reserved.