文献类型：期刊文献

英文题名：A fluorescent turn-on probe for visualizing lysosomes in hypoxic tumor cells

作者：Luo, Sihang[1,2,3];Liu, Yingchao[4];Wang, Feiyi[2,3];Fei, Qiang[2,3];Shi, Ben[2,3];An, Jiancai[2,3];Zhao, Chunchang[2,3];Tung, Chen-Ho[1]

机构：[1]Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China;[2]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China;[4]Shandong Univ, Prov Hosp, Dept Neurosurg, Jinan 250021, Peoples R China

年份：2016

卷号：141

期号：10

起止页码：2879

外文期刊名：ANALYST

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000376136100008)】；

基金：We gratefully acknowledge the financial support by the National Science Foundation of China (grant numbers 21172071, 21190033, 21372083), National 973 Program (2013CB733700) and Natural Science Foundation of Shandong Province (ZR2014HM069).

语种：英文

摘要：A fluorescent probe for fulfilling a lysosome targeting function in hypoxic tumor cells is reported, wherein azoreductase triggers a dramatic fluorescence enhancement and specific imaging of lysosomes in hypoxic cancer cells.