文献类型：期刊文献

中文题名：Mitochondria-targeted ratiometric fluorescent probes for micropolarity and microviscosity and their applications

英文题名：Mitochondria-targeted ratiometric fluorescent probes for micropolarity and microviscosity and their applications

作者：Jingjing Cui[1];Yuhua Yao[1];Cong Chen[1];Rui Huang[1];Weibing Zhang[1];Junhong Qian[1]

机构：[1]Shanghai Key Laboratory of Functional Materials Chemistry, School of Chemistry & Molecular Engineering, East China University of Science and Technology

年份：2019

卷号：30

期号：5

起止页码：1071

中文期刊名：Chinese Chemical Letters

外文期刊名：中国化学快报（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2019_2020】；PubMed;

基金：the National Natural Science Foundation of China(No.21576085)for financial support

语种：英文

中文关键词：Fluorescent;probe;Mitochondria;Microviscosity;Micropolarity

外文关键词：Fluorescent probe;Mitochondria;Microviscosity;Micropolarity

摘要：Two fluorescent“off-on”probes YYH1 and YYH2 were used for the detection of mitochondrial polarity and viscosity.Both probes have two emission bands:The peak of shorter wavelength was sensitive to the polarity,while that in longer wavelength region was sensitive to the viscosity,which enables us to detect medium polarity and viscosity simultaneously.The lg(Ishort/Ilong)of YYH1 exhibited linear relationship to the solvent polarity,while that of YYH2 was closely related to the solvent viscosity.Furthermore,both probes showed potential in bioimaging mitochondrial polarity or viscosity in living cells.
Two fluorescent "off-on" probes YYH1 and YYH2 were used for the detection of mitochondrial polarity and viscosity. Both probes have two emission bands:The peak of shorter wavelength was sensitive to the polarity, while that in longer wavelength region was sensitive to the viscosity, which enables us to detect medium polarity and viscosity simultaneously. The lg(Ishort/Ilong) of YYH1 exhibited linear relationship to the solvent polarity, while that of YYH2 was closely related to the solvent viscosity. Furthermore, both probes showed potential in bioimaging mitochondrial polarity or viscosity in living cells.