文献类型：期刊文献

英文题名：A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells

作者：Xu, Zheng[1];Xu, Lin[1];Zhou, Ji[1];Xu, Yufang[1];Zhu, Weiping[1];Qian, Xuhong[1]

机构：[1]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2012

卷号：48

期号：88

起止页码：10871

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000309666900016)】；

基金：We are grateful for the financial support from National Basic Research Program of China (973 Program, 2010CB126100), the National High Technology Research and Development Program of China (863 Program 2011AA10A207), the China 111 Project (Grant B07023), and the Shanghai Leading Academic Discipline Project (B507).

语种：英文

摘要：A new ratiometric fluorescence probe E1 based on an excited-state intramolecular proton transfer (ESIPT) mechanism for detection of hydrogen sulfide (H2S) is reported. E1 responds to H2S quickly and showed a 30-fold fluorescence enhancement in 2 minutes. Moreover, E1 can detect H2S quantitatively with a detection limit as low as 0.12 mu M in aqueous solution. Its potential for biological applications was confirmed by employing it for fluorescence imaging of H2S in living cells.