文献类型：期刊文献

英文题名：Sulfate radical-based oxidation of the antibiotics sulfamethoxazole, sulfisoxazole, sulfathiazole, and sulfamethizole: The role of five-membered heterocyclic rings

作者：Zhou, Lei[1,2];Yang, Xuerui[1];Ji, Yuefei[3];Wei, Jie[4]

机构：[1]East China Univ Sci & Technol, State Environm Protect Key Lab Environm Risk Asse, Sch Resources & Environm Engn, Shanghai 200237, Peoples R China;[2]Shanghai Inst Pollut Control & Ecol Secur, Shanghai 200092, Peoples R China;[3]Nanjing Agr Univ, Coll Resources & Environm Sci, Nanjing 210095, Jiangsu, Peoples R China;[4]Suzhou Univ Sci & Technol, Sch Chem Biol & Mat Engn, Suzhou 215009, Peoples R China

年份：2019

卷号：692

起止页码：201

外文期刊名：SCIENCE OF THE TOTAL ENVIRONMENT

收录：;EI(收录号：20193007235296);WOS:【SCI-EXPANDED(收录号:WOS:000484994700021)】；

基金：The authors gratefully acknowledge the financial support from the Natural Science Foundation of Jiangsu Province-China (Grant No. BK20160709), the National Natural Science Foundation of China (Grant No. 21607077), the Fundamental Research Funds for Central Universities (Grant No. KJQN201741), and the Nanjing Agricultural University International Cooperation Project (Grant No. 2018-EU-10). The content of the paper does not necessarily represent the views of the funding agencies.

语种：英文

外文关键词：Heterocyclic rings; Persulfate; Sulfamethoxazole; Sulfate radical; Sulfonamide antibiotics; Transformation

摘要：The widespread occurrence of sulfonamides (SAs) in natural waters, wastewater, soil and sediment has raised increasing concerns about their potential risks to human health and ecological systems. Sulfate radical (SO4 center dot-)based advanced oxidation processes (SR-AOPs) have become promising technologies to remove such contaminants in the environment. The present study systematically investigated the degradation of four selected SAs with different five-membered heterocyclic rings, namely, sulfamethoxazole (SMX), sulfisoxazole (SIX), sulfathiazole (STZ), and sulfamethizole (SMT), by thermo-activated persulfate (PS) process, and the role of heterocyclic rings was assessed particularly. The results revealed that all the selected SAs could be degraded efficiently by thermo-activated PS process and their decay rates were appreciably increased with increasing temperature. For instance, degradation rates of STZ increased from 0.3 x 10(-3) to 19.5 x 10(-3) min(-1) as the temperature was increased from 30 to 60 degrees C. Under the same experimental conditions, the degradation rates of SAs followed the order of SIX > SMX approximate to STZ > SMT, which was in accordance with decay rates of their R-NH2 moieties. Kinetic results indicated that five-membered heterocyclic rings could serve as reactive moieties toward SO4 center dot- attack, which were confirmed by frontier electron density (FED) calculations. Based on the transformation products identified by high-resolution mass spectrometry (HR-MS), five different oxidation pathways, including hydroxylation, aniline moiety oxidation, dimerization, sulfonamide bond cleavage, and heterocyclic ring oxidation/cleavage were proposed. Moreover, the degradation efficiency in real surface water (RSW) was found to be slightly slower than that in artificial surface water (ASW), suggesting that SR-AOPs could be an efficient approach for remediation of soil and water contaminated by these SAs. (C) 2019 Elsevier B.V. All rights reserved.