文献类型：会议论文

英文题名：Understanding Drug Delivery from a System Perspective: Concept and Demonstration

作者：Yin, R. X.[1,2];Bai, M. R.[1];Zhang, B.[2];Wang, K. M.[2];Zhang, H. B.[1];Yang, S. M.[1];Zhang, W. J.[1];Wang, J. W.[2,3]

机构：[1]East China Univ Sci & Technol, Sch Mech & Power Engn, Shanghai, Peoples R China;[2]Univ Saskatchewan, Div Biomed Engn, Saskatoon, SK, Canada;[3]Univ Hong Kong, Dept Ind & Mfg Syst Engn, Hong Kong, Hong Kong, Peoples R China

会议论文集：12th IEEE Annual International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS)

会议日期：APR 09-12, 2017

会议地点：Los Angeles, CA

语种：英文

外文关键词：drug delivery; drug supply chain; system perspcetive; glucose-responsive

摘要：In our work, for the first time, we view drug delivery as drug supply chain, and analyze drug supply chain from a system perspective. A glucose-responsive insulin delivery microgel is taken as an example to have a system view of it for a better understanding of its behavior. The benefit of viewing drug delivery as a supply chain system is the possibility of applying the advanced design (such as FBS model) and control technology (such as robust control) well known in mechanical engineering to drug supply systems, which may significantly improve the design and control of a drug supply system to further improve the performance and safety of drug delivery.