文献类型：期刊文献

英文题名：Influence of Host-Guest Interaction between Chiral Selectors and Probes on the Enantioseparation Properties of Graphene Oxide Membranes

作者：Meng, Chenchen[1,2];Zhang, Shaoze[1,2,3,4];Chen, Qibin[1,2];Li, Xiaoxiao[1,2];Liu, Honglai[1,2]

机构：[1]East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[3]Kunming Univ Sci & Technol, Natl Engn Lab Vacuum Met, Kunming 650093, Yunnan, Peoples R China;[4]Kunming Univ Sci & Technol, Engn Lab Adv Battery & Mat Yunnan Prov, Kunming 650093, Yunnan, Peoples R China

年份：2020

卷号：12

期号：9

起止页码：10893

外文期刊名：ACS APPLIED MATERIALS & INTERFACES

收录：;EI(收录号：20201008255353);WOS:【SCI-EXPANDED(收录号:WOS:000518702300086)】；

基金：We acknowledge the National Natural Science Foundation of China (no. 21576079, and 91834301), the 111 Project of Ministry of Education of China (no. B08021), and the Fundamental Research Funds of the Central Universities of China for the financial support.

语种：英文

外文关键词：enantioseparation; graphene oxide membranes; binding affinity; density of functional theory; noncovalent interaction

摘要：Graphene oxide (GO)-based membranes have displayed superior performances in the chiral resolution compared with conventional polymer-based and inorganic membranes. However, the effect of the host-guest interaction between chiral selectors and probes on the enantioseparation properties of GO-based membranes remains to be established. In this work, L-phenylalanine (L-Phe, as the chiral selector)-modified GO-based (L-Phe-GO) membranes were fabricated, and their enantioseparation performances toward various enantiomers, that is, D- and L-phenylalanine (D- and L-Phe), D- and L-methionine (D- and L-Met), N-acyl-D-phenylalanine (N-aryl-D-Phe) and N-acyl-L-phenylalanine (N-acyl-L-Phe), and N-aryl-D-methionine (N-acyl-D-Met) and N- acyl-L-methionine (N-acyl-L-Met), were detected. Results show that (i) L-Phe is preferential to transport aenantiomers relative to Lenantiomers; (ii) as far as aenantiomers are concerned, the D-Phe-like enantiomers move faster than D-Met-like ones through the L- Phe-GO membrane owing to their different host-guest interactions. The strength of interactions between chiral selectors and probes was further confirmed from both experimental and theoretical standpoints. In the former case, the enantioselective adsorption of L-Phe-GO nanosheets toward the aforementioned enantiomers demonstrates that L-Phe delivers a higher adsorption capacity to L-enantiomers relative to L-enantiomers, and meanwhile, D-Met-like enantiomers are better than D-Met-like enantiomers in the adsorption capacity. In the latter case, the chiral separation mechanism is clarified using the periodical density functional theory (DFT) calculation, indicating that L-Phe interacts with D-enantiomers more strongly than L-enantiomers. Especially, our calculations unveil that the difference in the interaction strength is principally dominated by the nonstereoselective interactions between chiral probes and the GO surface. Therefore, our findings suggest that the nonstereoselective weak interaction can be employed to improve the enantioselectivity of GO-based membranes.