文献类型：期刊文献

英文题名：Synthesis of triarylphosphines from arylammonium salts via one-pot transition-metal-free C-P coupling

作者：Zhang, Lei[1];Liu, Chengyu[1];Yang, Lei[1];Cao, Liming[1];Liang, Chaoming[2];Sun, Maolin[2];Ma, Yueyue[2];Cheng, Ruihua[2];Ye, Jinxing[1,2]

机构：[1]East China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Sch Pharm, Minist Educ, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]Guangdong Univ Technol, Sch Biomed & Pharmaceut Sci, Guangzhou 510006, Peoples R China

年份：2022

卷号：20

期号：19

起止页码：3897

外文期刊名：ORGANIC & BIOMOLECULAR CHEMISTRY

收录：;EI(收录号：20222112133119);WOS:【SCI-EXPANDED(收录号:WOS:000788234100001)，CCR-EXPANDED(收录号:WOS:000788234100001)】；

基金：This work was partially supported by the National Natural Science Foundation of China (22071056 and 22001070) and the Shanghai Sailing Program (20YF1410400).

语种：英文

外文关键词：Phosphorus compounds - Salts - Sulfur compounds

摘要：A nucleophilic aromatic substitution (SNAr) reaction that allowed transition-metal-free C-P bond construction via C-N bond cleavage was developed. The coupling between aryltrimethylammonium salts and secondary phosphines from the in situ reduction of diarylphosphine oxides led to the formation of diverse triarylphosphines with various functional groups. This one-pot process was not only a pertinent SNAr precedent but also a favorable transition-metal-free alternative for C-P coupling.