文献类型：期刊文献

英文题名：Optimization of polystyrene-supported triphenylphosphine catalysts for aza-Morita-Baylis-Hillman reactions

作者：Zhao, LJ; Kwong, CKW; Shi, M; Toy, PH

机构：[1]E China Univ Sci & Technol, Sch Chem & Pharmaceut, Shanghai 200237, Peoples R China;[2]Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China

年份：2005

卷号：61

期号：51

起止页码：12026

外文期刊名：TETRAHEDRON

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000233784300002)，CCR-EXPANDED(收录号:WOS:000233784300002)】；

语种：英文

外文关键词：Morita-Baylis-Hillman reaction; polymer-supported reagents; triphenylphosphine; polystyrene

摘要：A series of polar group functionalized polystyrene-supported phosphine reagents were examined as catalysts in the aza-Morita-Baylis-Hillman reactions of N-tosyl arylimines and a variety of Michael acceptors with the aim of identifying the optimal polymer/solvent combination. For these reactions JandaJel-PPh3 (1 mmol PPh3/g loading) resin containing methoxy groups (JJ-OMe-PPh3) on the polystyrene backbone in THF solvent provided the highest yield of all the catalyst/solvent combinations examined. The methyl ether groups were incorporated into JJ-OMe-PPh3 using commercially available 4-methoxystyrene, and thus such polar polystyrene resins are easily accessible and should find utility as nucleophilic catalyst supports. (c) 2005 Elsevier Ltd. All rights reserved.