文献类型：期刊文献

英文题名：Synthesis of Diiodinated All-Carbon 3,3′-Diphenyl-1,1′-ispirobiindene Derivatives via Cascade Enyne Cyclization and Electrophilic Aromatic Substitution

作者：Li, Quanzhe[1,2];Yu, Liuzhu[1,2];Wei, Yin[3];Shi, Min[1,2,3,4]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat, Sch Chem & Mol Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Inst Fine Chem, Sch Chem & Mol Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, Ctr Excellence Mol Synth, State Key Lab Organometall Chem, 345 Ling Ling Rd, Shanghai 200032, Peoples R China;[4]Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen 518000, Guangdong, Peoples R China

年份：2019

卷号：84

期号：14

起止页码：9282

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000476957000042)，CCR-EXPANDED(收录号:WOS:000476957000042)】；

基金：We are grateful for the financial support from the National Basic Research Program of China [(973)-2015CB856603], the Strategic Priority Research Program of the Chinese Academy of Sciences (grant no. XDB20000000) and sioczz201808, the National Natural Science Foundation of China (20472096, 21372241, 21572052, 20672127, 21421091, 21372250, 21121062, 21302203, 21772037, 21772226, 20732008, and 21861132014), the Fundamental Research Funds for the Central Universities 222201717003, and the Shenzhen Nobel Prize Scientists Laboratory Project.

语种：英文

摘要：A synthetic method for the construction of diiodinated all-carbon spirobiindene derivatives has been developed from the reaction of propargyl alcohol-tethered alkylidenecyclopropanes with iodine. The reaction proceeded through an iodination-initiated cascade intramolecular enyne cyclization and electrophilic aromatic substitution reaction process in 1,2-dichloroethane upon heating, giving desired spirocyclic products in moderate to excellent yields. Further transformation of the obtained products has also been presented.