文献类型：期刊文献

英文题名：Rational design of a fast and selective near-infrared fluorescent probe for targeted monitoring of endogenous nitric oxide

作者：Tang, Junma;Guo, Zhiqian[1];Zhang, Yutao;Bai, Bing;Zhu, Wei-Hong

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Key Lab Adv Mat, Shanghai 200237, Peoples R China; East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2017

卷号：53

期号：76

起止页码：10520

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000411589300008)】；

基金：This work was supported by the National Key Research and Development Program (No. 2017YFC0906902), Excellent Young Scholars (21622602), Distinguished Young Scholars (21325625), the Key Project (21636002), the NSFC/China, the Oriental Scholarship, the Scientific Committee of Shanghai (14ZR1409700 and 15XD1501400), the Fok Ying Tong Education Foundation (142014), and the Fundamental Research Funds for the Central Universities.

语种：英文

摘要：The real-time monitoring of nitric oxide (NO) at the subcellular level is still a great challenge. To attain this goal, we developed a fast and selective near-infrared (NIR)fluorescent probe for the targeted tracing of endogenous NO. This probe possesses vital features for the real-time detection of intracellular NO including a significant turn-on NIR response, high specificity, and a fast response by a controlled photoinduced electron transfer (PET) process, which is applicable to the real-time monitoring of endogenous NO in mitochondria.