文献类型：期刊文献

英文题名：One-pot synthesis of 1 H-benzimidazole derivatives using thiamine hydrochloride as a reusable organocatalyst

作者：Lei, Min[1]; Ma, Lei[2]; Hu, Lihong[1,2,3]

机构：[1] Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Shanghai, China; [2] School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China; [3] Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

年份：2012

卷号：42

期号：20

起止页码：2981

外文期刊名：Synthetic Communications

收录：EI(收录号：20242616517356)

语种：英文

外文关键词：Aldehydes - Aromatic compounds - Dimethylformamide - Metal ions - Metal recovery

摘要：A simple and efficient one-pot synthesis of 1H-benzimidazole derivatives using thiamine hydrochloride (VB1) as the organocatalyst from o-phenylenediamine and aldehyde in dimethylformamide is described. Compared to classical reaction conditions, this new method consistently has the advantages of excellent yields, metal-ion-free procedure, and good recovery and reusablity of catalyst. ? 2012 Taylor & Francis Group, LLC.