文献类型：期刊文献

英文题名：Synthesis of Typical Isocopalane Diterpenes: ent-Spongian-16-one, ent-Isoagatholactone, and Anisodorin 5

作者：Rena, Jiangmeng[1];Zhao, Pu[1];Xiao, Xiong[1];Chen, Tianqi[1];Zeng, Bu-Bing[1,2]

机构：[1]East China Univ Sci & Technol, Sch Pharm, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Synthet Chem Nat Subst, 345 Lingling Rd, Shanghai 200232, Peoples R China

年份：2016

卷号：48

期号：23

起止页码：4161

外文期刊名：SYNTHESIS-STUTTGART

收录：;EI(收录号：20163402737822);WOS:【SCI-EXPANDED(收录号:WOS:000389329500021)】；

基金：This work was financially supported by the National Natural Science Foundation of China (21302053), the Science and Technology Commission of Shanghai Municipality (14DZ1900102), and the Fundamental Research Funds for the Central University (WY1113007).

语种：英文

外文关键词：terpenoids; total synthesis; anisodorin 5; spongianone; isoagatholactone

摘要：A synthetic approach to the isocopalane diterpenes ent-spongian-16-one, ent-isoagatholactone, and anisodorin 5 is presented. ent-Spongian-16-one was prepared by using a tricyclic diterpene building block as the starting material. Furthermore, ent-spongian-16-one was easily converted into ent-isoagatholactone and anisodorin 5 through organic transformations.