文献类型：期刊文献

英文题名：Super-resolution imaging of lysosomes with a nitroso-caged rhodamine

作者：He, Haihong[1];Ye, Zhiwei[2];Zheng, Ying[2];Xu, Xiu[1];Guo, Chunlei[1];Xiao, Yi[2];Yang, Wei[2];Qian, Xuhong[1];Yang, Youjun[1]

机构：[1]East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Liaoning, Peoples R China

年份：2018

卷号：54

期号：23

起止页码：2842

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000428844500003)】；

基金：The work is financially supported by the National Natural Science Foundation of China (No. 21372080, 21572061, 21236002, 21376038, 21421005, 21576040 and 21776037), National Basic Research Program of China (No. 2013CB733702) and the Fundamental Research Funds for the Central Universities (No. WY1514053, WY1516017 and DUT17LK43).

语种：英文

摘要：Caged-fluorophores are potentially suitable for photo-activated localization microscopy (PALM) for super-resolution imaging. N-Nitroso is a simple and robust photo-cage with biocompatible nitric oxide as the only byproduct upon photolysis. We herein reported a novel PALM probe (NOR535) for super-resolution imaging of lysosomes with high localization precision.