文献类型：期刊文献

英文题名：Validation of the Application of Solid Contact Ion-Selective Electrode for Off-Body Sweat Ion Monitoring

作者：Liu, Huixin[1,2,3];Gu, Zhen[4];Liu, Yuan[5];Xiao, Xinxin[6];Xiu, Guangli[1,2,3]

机构：[1]East China Univ Sci & Technol, Shanghai Environm Protect Key Lab Environm Stand, Sch Resources & Environm Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Resources & Environm Engn, State Environm Protect Key Lab Environm Risk Asse, Shanghai 200237, Peoples R China;[3]Shanghai Inst Pollut Control & Ecol Secur, Shanghai 200092, Peoples R China;[4]East China Univ Sci & Technol, Sch Informat Sci & Engn, Dept Automat, Shanghai 200237, Peoples R China;[5]COFCO Corp, Chao Yang Men South St 8, Beijing 100020, Peoples R China;[6]Tech Univ Denmark, Dept Chem, DK-2800 Lyngby, Denmark

年份：2022

卷号：12

期号：4

外文期刊名：BIOSENSORS-BASEL

收录：;EI(收录号：20231213759364);WOS:【SCI-EXPANDED(收录号:WOS:000786052100001)】；

基金：This work was supported by Shanghai Science and Technology Commission (19DZ1205001, 20DZ1204006) and Shanghai Municipal Bureau of Ecology and Environment [2021]-46. Z.G. acknowledges a National Key Research and Development Program of China (grant no. 2021YFC2101101). X.X. acknowledges a Villum Experiment (grant no. 35844).

语种：英文

外文关键词：ion-selective electrode; ICP-OES; sweat ion; off-body

摘要：The solid contact ion-selective electrode (ISE) is a promising skin-interfaced monitoring system for sweat ions. Despite a growing number of on-body usages of ISE with fancy new materials and device fabrications, there are very few reports attempting to validate ISE results with a gold standard technique. For this purpose, this work uses inductively coupled plasma-optical emission spectrometry (ICP-OES) as a reference technique to conduct a direct evaluation of the sweat sodium and potassium ion levels obtained by ISE in an off-body approach. Eight healthy male subjects were recruited to collect exercise-induced sweat. It was found that sweat sodium and potassium ions present a rather wide concentration range. The sweat sodium concentration did not vary greatly in an exercise period of half an hour, while the sweat potassium concentration typically decreased with exercise. Mineral drink intake had no clear impact on the sweat sodium level, but increased the sweat potassium level. A paired t-test and mean absolute relative difference (MARD) analysis, a method typically used for evaluating the performance of glucometers, was employed to compare the results of ISE and ICP-OES. The statistical analysis validated the feasibility of ISE for measuring sweat ions, although better accuracy is required. Our data suggests that overweight subjects are likely to possess a higher sweat sodium level.