文献类型：期刊文献

英文题名：Rheology and Adhesion of Poly(acrylic acid)/Laponite Nanocomposite Hydrogels as Biocompatible Adhesives

作者：Shen, Muxian[1];Li, Li[1];Sun, Yimin[1];Xu, Jun[1];Guo, Xuhong[1];Prud'homme, Robert K.[2]

机构：[1]E China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[2]Princeton Univ, Dept Chem Engn, Princeton, NJ 08544 USA

年份：2014

卷号：30

期号：6

起止页码：1636

外文期刊名：LANGMUIR

收录：;EI(收录号：20140917390428);WOS:【SCI-EXPANDED(收录号:WOS:000331774400020)】；

基金：We gratefully acknowledge the National Natural Science Foundation of China (51273063, 51003028, and 11076002/A06), the Fundamental Research Funds for the Central Universities, the Higher School Specialized Research Fund for the Doctoral Program (20110074110003), and the 111 Project Grant (B08021) for support of this work.

语种：英文

外文关键词：Ascorbic acid - Biocompatibility - Adhesion - Elasticity - Gels - Nanocomposites - Free radical polymerization - Free radicals - Tissue engineering - Carboxylic acids - Solutions

摘要：Biocompatible nanocomposite hydrogels (NC gels) consisting of poly(acrylic acid) (PAA) and nanosized clay (Laponite) were successfully synthesized by in situ free-radical polymerization of acrylic acid (AA) in aqueous solutions of Laponite. The obtained NC gels were uniform and transparent. Their viscosity, storage modulus G', and loss modulus G '' increased significantly upon increasing the content of Laponite and the dose of AA, while exhibiting a maximum with increasing the neutralization degree of AA. They showed tunable adhesion by changing the dose of Laponite and monomer as well as the neutralization degree of AA, as determined by 180 degrees peel strength measurement. The maximal adhesion was shown when reaching a balance between cohesion and fluidity. A homemade Johnson-Kendall-Roberts (JKR) instrument was employed to study the surface adhesion behavior of the NC gels. The combination of peel strength, rheology, and JKR measurements offers the opportunity of insight into the mechanism of adhesion of hydrogels. The NC gels with tunable adhesion should be ideal candidates for dental adhesive, wound dressing, and tissue engineering.