文献类型：期刊文献

英文题名：Spin-Casting Polymer Brush Films for Stimuli-Responsive and Anti-Fouling Surfaces

作者：Xu, Binbin[1];Feng, Chun[1];Hu, Jianhua[2];Shi, Ping[3];Gu, Guangxin[2];Wang, Lei[2];Huang, Xiaoyu[1]

机构：[1]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Synthet & Self Assembly Chem Organ Funct, 345 Lingling Rd, Shanghai 200032, Peoples R China;[2]Fudan Univ, Dept Macromol Sci, State Key Lab Mol Engn Polymers, 220 Handan Rd, Shanghai 200433, Peoples R China;[3]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2016

卷号：8

期号：10

起止页码：6685

外文期刊名：ACS APPLIED MATERIALS & INTERFACES

收录：;EI(收录号：20161402183603);WOS:【SCI-EXPANDED(收录号:WOS:000372479300046)】；

基金：The authors thank the financial support from National Basic Research Program of China (2015CB931900), International Science & Technology Cooperation Program of China (2014DFE40130), National Natural Science Foundation of China (21474127 and 51373035), and Shanghai Scientific and Technological Innovation Project (13ZR1464800 and 14520720100).

语种：英文

外文关键词：polymer brush; thin film; stimuli-responsive; antifouling; spin-casting

摘要：Surfaces modified with amphiphilic polymers can dynamically alter their physicochemical properties in response to changes of their environmental conditions; meanwhile, amphiphilic polymer coatings with molecular hydrophilic and hydrophobic patches, which can mitigate biofouling effectively, are being actively explored as advanced coatings for antifouling materials. Herein, a series of well-defined amphiphilic asymmetric polymer brushes containing hetero side chains, hydrophobic polystyrene (PS) and hydrophilic poly(ethyiene glycol) (PEG), was employed to prepare uniform thin films by spin-casting. The properties of these films were investigated by water contact angle, X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), and quartz crystal microbalance (QCM). AFM showed smooth surfaces for all films with the roughness less than 2 nm. The changes in water contact angle and C/O ratio (XPS) evidenced the enrichment of PEG or PS chains at film surface after exposed to selective solvents, indicative of stimuli- responsiveness. The adsorption of proteins on PEG functionalized surface was quantified by QCM and the results verified that amphiphilic polymer brush films bearing PEG chains could lower or eliminate protein-material interactions and resist to protein adsorption. Cell adhesion experiments were performed by using HaCaT cells and it was found that polymer brush films possess good antifouling ability.