文献类型：期刊文献

英文题名：Access to Isoquinolines and Isoquinolin-3-ols via Rh(III)-Catalyzed Coupling/Cyclization Cascade Reaction of Arylimidates and Diazo Compounds

作者：Li, Xing Guang;Sun, Min;Jin, Qiao;Liu, Kai;Liu, Pei Nian[1]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai Key Lab Funct Mat Chem, Meilong Rd 130, Shanghai 200237, Peoples R China; E China Univ Sci & Technol, Inst Fine Chem, Meilong Rd 130, Shanghai 200237, Peoples R China

年份：2016

卷号：81

期号：9

起止页码：3901

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：;EI(收录号：20162102412429);WOS:【SCI-EXPANDED(收录号:WOS:000375890100047)，CCR-EXPANDED(收录号:WOS:000375890100047)】；

基金：This work was supported by NSFC (Project Nos. 21421004, 21190033, 21372072, and 21561162003), NCET (NCET-13-0798), the Basic Research Program of the Shanghai Committee of Sci. & Tech. (Project No. 13M1400802), the Programme of Introducing Talents of Discipline to Universities (B16017), the Program for Eastern Scholar Distinguished Professor, and the Fundamental Research Funds for the Central Universities.

语种：英文

外文关键词：Rhodium compounds

摘要：A Rh(III)-catalyzed coupling/cyclization cascade reaction is described, which involves arylimidates and diazo compounds and proceeds via intermolecular C-C bond formation and subsequent intramolecular C-N bond formation. Mechanistic investigation revealed that the reaction is a two-step process: the initial Rh(III)-catalyzed coupling/cyclization proceeds very fast and the following dehydration is rather slow. The reaction provides a direct approach to isoquinolines and isoquinolin-3-ols without any oxidants.