文献类型：期刊文献

英文题名：Total Syntheses of Eudistomins Y1-Y7 by an Efficient One-Pot Process of Tandem Benzylic Oxidation and Aromatization of 1-Benzyl-3,4-dihydro-β-Carbolines

作者：Trieu, Tien Ha[1];Dong, Jing[1];Zhang, Qiang[1];Zheng, Bo[1];Meng, Tian-Zhuo[1];Lu, Xia[1];Shi, Xiao-Xin[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Dept Pharmaceut Engn, Shanghai 200237, Peoples R China

年份：2013

卷号：2013

期号：16

起止页码：3271

外文期刊名：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000320175200010)，CCR-EXPANDED(收录号:WOS:000320175200010)】；

基金：The authors thank the National Natural Science Foundation of China (NSFC) (grant number 20972048) and the Shanghai Educational Development Foundation (The Dawn Program, grant number 03SG27) for financial support for this work. T. H. T. thanks the Ministry of Education and Training, Vietnam for financial support.

语种：英文

外文关键词：Natural products; Alkaloids; Total synthesis; Nitrogen heterocycles; Aromatization

摘要：The first total synthesis of eudistomin Y-7 (7) and total syntheses of eudistomins Y-1-Y-6 (1-6) are described. An efficient room-temperature conversion of 1-benzyl-3,4-dihydro-beta-carbolines (11) into 1-benzoyl-beta-carbolines (14) by a one-pot process of tandem benzylic oxidation and aromatization as the key step of these total syntheses was also studied in detail.