文献类型：期刊文献

英文题名：Activatable BODIPY-chromene NIR-II probes with small spectral crosstalk enable high-contrast in vivo bioimaging

作者：Zhang, Liao;Yan, Chenxu;Zhang, Yutao;Ma, Dun;Huang, Jialiang;Zhao, Zijun;Tao, Yining;Liu, Caiqi;Li, Juan;Zhu, Wei-Hong;Guo, Zhiqian[1]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat, Feringa Nobel Prize Scientist Joint Res Ctr, Sch Chem & Mol Engn,Inst Fine Chem, Shanghai Shanghai, Peoples R China; East China Univ Sci & Technol, Inst Fine Chem, Feringa Nobel Prize Scientist Joint Res Ctr, Sch Chem & Mol Engn,Joint Int Res Lab Precis Chem, Shanghai 200237, Peoples R China

年份：2023

卷号：59

期号：54

起止页码：8388

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;EI(收录号：20232614325617);WOS:【SCI-EXPANDED(收录号:WOS:001004457800001)】；

基金：This work was supported by NSFC/China (22225805 and 32121005), Shanghai Pujiang Program (grant 21PJD038), and Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell Metabolism (Shanghai Municipal Education Commission, grant 2021 Sci & Tech 03-28).

语种：英文

外文关键词：Bioimaging - Chromophores - Crosstalk - Infrared devices

摘要：Herein, we design a novel "crossbreeding" dye (BC-OH) within the second near-infrared (NIR-II) window based on BODIPY and chromene chromophores. BC-OH can serve as a platform to construct activatable NIR-II probes with small spectral crosstalk, thereby making a breakthrough in imaging in vivo H2O2 fluctuation in an APAP-induced liver injury model with high signal-to-background ratio.