文献类型：期刊文献

英文题名：An aza-BODIPY based near-infrared fluorescent probe for sensitive discrimination of cysteine/homocysteine and glutathione in living cells

作者：Xiang, Hui-Jing[1,2];Huijun Phoebe Tham[1];Minh Duc Nguyen[1];Phua, Soo Zeng Fiona[1];Lim, Wei Qi[1];Liu, Jin-Gang[2];Zhao, Yanli[1,3]

机构：[1]Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, 21 Nanyang Link, Singapore 637371, Singapore;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[3]Nanyang Technol Univ, Sch Mat Sci & Engn, 50 Nanyang Ave, Singapore 639798, Singapore

年份：2017

卷号：53

期号：37

起止页码：5220

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000400858400036)】；

基金：We are grateful for the financial support from the National Nature Science Foundation of China (no. 21271072 and 21571062), the Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning, the Fundamental Research Funds for the Central Universities (no. 222201717003), and the SingHealth-NTU Research Collaborative Grant (no. SHS-NTU/009/2016). H.-J. Xiang acknowledges the scholarship support from the Chinese Scholarship Council.

语种：英文

摘要：Discriminative detection of glutathione (GSH) from cysteine/homocysteine (Cys/Hcy) is achieved through two emission channel analysis using a stable, highly sensitive, and selective near-infrared fluorescent probe that bears 7-nitrobenzo-2-oxa-1,3-diazole and aza-BODIPY units. The probe was successfully applied for simultaneous determination of GSH and Cys/Hcy in living cells.