文献类型：期刊文献

英文题名：A highly selective space-folded photo-induced electron transfer fluorescent probe for carbonic anhydrase isozymes IX and its applications for biological imaging

作者：Zhang, Shenyi[1];Yang, Chunmei[1];Lu, Weiqiang[1];Huang, Jin[1];Zhu, Weiping[1];Li, Honglin[1];Xu, Yufang[1];Qian, Xuhong[1]

机构：[1]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China

年份：2011

卷号：47

期号：29

起止页码：8301

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000292980900029)】；

基金：We thank Prof. Seppo Parkkila (University of Tampere, Finland) for providing the plasmid of carbonic anhydrase IX. This work is financially supported by the National Basic Research Program of China (010CB126100), the National High Technology Research and Development Program of China (2011AA10A207), the National Natural Science Foundation of China (21076077), the China 111 Project (B07023), the Shanghai Leading Academic Discipline Project (B507) and the Fundamental Research Funds for the Central Universities.

语种：英文

摘要：The first highly selective and sensitive fluorescent probe Z1 for detection of carbonic anhydrase IX (CA IX) over isoforms CA I and CA II was developed. As demonstrated, Z1 worked effectively in both enzymatic systems and living hypoxia cells.