文献类型：期刊文献

英文题名：Polyamide membranes with structural homogeneity regulated by alkyl chain engineering for precise molecular sieving

作者：Yang, Hui[1,2];Wang, Dan[1,2];Gu, Shuyun[1,2];Zhou, Linlong[1,2];Li, Siyao[1,2];Xu, Zhi[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem Engn, State Key Lab Chem Engn, Shanghai, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem Engn, Shanghai Key Lab Multiphase Mat Chem Engn, Shanghai, Peoples R China

年份：2026

外文期刊名：AICHE JOURNAL

收录：;EI(收录号：20260620012508);WOS:【SCI-EXPANDED(收录号:WOS:001669762100001)】；

基金：National Key Research and Development Program of China, Grant/Award Number: 2024YFB3815600; National Natural Science Foundation of China, Grant/Award Numbers: 22308099, 22478109, 23FAA02066

语种：英文

外文关键词：alkyl chain engineering; diffusion-reaction synergy; interfacial polymerization; organic solvent nanofiltration; precise molecular sieving

摘要：Precise sieving of structurally similar solutes in organic solvents is crucial for chemical industries such as pharmaceutical synthesis and petroleum refining. However, it remains technically challenging due to their similar physicochemical properties. Achieving this with organic solvent nanofiltration (OSN) requires membranes with narrow pore-size distribution and tailored surface chemistry. Herein, we report an additive-free strategy to prepare ultrathin, structurally homogeneous polyamide (PA) nanofilms via alkyl chain engineering during interfacial polymerization (IP). Alkyl chains synergistically regulate the diffusion kinetics and the reaction process: they enable rapid, uniform amine supply while introducing steric hindrance that moderates polycondensation. This dual regulation yields a structurally homogeneous PA layer with sub-nanometer pores. The optimized membrane shows a sharp rejection curve and effectively separates antibiotics, demonstrating promise for pharmaceutical purification. This work advances the understanding of diffusion-reaction synergy in IP and offers a facile strategy for precision separation membranes.