文献类型：期刊文献

英文题名：Multicomponent Cascade Synthesis of Trifluoroethyl Isoquinolines from Alkynes and Vinyl Azides

作者：Liu, Kai;Chen, Shuang;Li, Xing Guang;Liu, Pei Nian[1]

机构：[1]E China Inst Theoret Phys, Key Lab Adv Mat, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China; E China Inst Theoret Phys, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2016

卷号：81

期号：1

起止页码：265

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：;EI(收录号：20160201789567);WOS:【SCI-EXPANDED(收录号:WOS:000367701900028)，CCR-EXPANDED(收录号:WOS:000367701900028)】；

基金：This work was supported by the National Natural Science Foundation of China (Project Nos. 21421004, 21172069, 21372072 and 21190033), NCET (NCET-13-0798), the Basic Research Program of the Shanghai Committee of Sci. & Tech. (Project No. 13M1400802), and the Fundamental Research Funds for the Central Universities.

语种：英文

外文关键词：Chemical reactions - Rhodium compounds - Copper compounds

摘要：A multicomponent cascade reaction is described that provides concise access to the trifluoroethyl isoquinolines using a Rh(III)-Cu(II) bimetallic system and readily available Togni's reagent. The system tolerates various vinyl azides and internal alkynes. Experimental results suggest that Togni's reagent might act as a CF3 radical supplier.