文献类型：期刊文献

英文题名：Copper(I)-Mediated Direct Trifluoromethylthiolation of Allylic Halides with Elemental Sulfur and (Trifluoromethyl)trimethylsilane

作者：Li, Jue[1];Wang, Peiqiang[1];Xie, Fei-Fei[1];Yang, Xi-Gang[1];Song, Xiao-Nan[1];Chen, Wei-Dong[2];Ren, Jiangmeng[1];Zeng, Bu-Bing[1,3]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Synthet Chem Nat Subst, Shanghai 200032, Peoples R China

年份：2015

卷号：2015

期号：16

起止页码：3568

外文期刊名：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000355265000020)，CCR-EXPANDED(收录号:WOS:000355265000020)】；

基金：We thank the National Natural Science Foundation of China (21302053) for the generous financial support. We are also grateful for the financial support from the Fundamental Research Funds for the Central University (WY111307).

语种：英文

外文关键词：Synthetic methods; Allylic compounds; Copper; Fluorine; Sulfur; Reaction mechanisms

摘要：A new method has been developed for the copper-mediated trifluoromethylthiolation of allylic halides by using potassium fluoride, elemental sulfur, and (trifluoromethyl)trimethylsilane in anhydrous N,N-dimethylformamide. This protocol provides facile access to a variety of allylic trifluoromethyl thioethers in moderate to good yields under mild, ligand-free reaction conditions.