文献类型：期刊文献

英文题名：Spectrometric Study on the Interaction of Dodecyltrimethylammonium Bromide with Curcumin

作者：Ke, Dan[1];Wang, Xiaoyong[1];Yang, Qianqian[1];Niu, Yumeng[1];Chai, Shaohu[1];Chen, Zhiyun[1];An, Xueqin[1];Shen, Weiguo[1]

机构：[1]E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China

年份：2011

卷号：27

期号：23

起止页码：14112

外文期刊名：LANGMUIR

收录：;EI(收录号：20114914574895);WOS:【SCI-EXPANDED(收录号:WOS:000297427500022)】；

基金：This project is sponsored by the National Natural Science Foundation of China (Grant 21173081), the Natural Science Foundation of Shanghai (Grant 11ZR1408600), the Fundamental Research Funds for the Central Universities (Grant WK0914037), and the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry of China.

语种：英文

外文关键词：Surface active agents - Sodium compounds

摘要：The interaction between dodecyltrimethylammonium bromide (DTAB) and curcumin has been studied in pH 5.0 sodium phosphate buffer using absorption and fluorescence measurements. With increasing DTAB concentration (C-DTAB) from 0 to 20 mM, the absorption peak of curcumin at 430 nm, corresponding to the conjugated structure of curcumin, first weakens gradually into a shoulder but increases back into one peak with much higher absorption intensity. On the contrary, as C-DTAB increases, the initial small absorption shoulder of curcumin at 355 nm, corresponding to the feruloyl unit of curcumin, first increases gradually into a clear peak but decreases back into one shoulder until almost disappeared finally. By remaining at nearly the same wavelength, the fluorescence of curcumin first decreases at C-DTAB lower than 5 mM and then increases gradually up to C-DTAB = 10 mM, which is followed by sharp increases of fluorescence intensity with marked blue-shifts at higher C-DTAB. The values of anisotropy and microviscosity of curcumin obtained from the fluorescence polarization technique also showed pronounced changes at different surfactant concentrations. The interaction mechanisms of DTAB with curcumin have been presented at low, intermediate, and high surfactant concentrations, which is relating to interaction forces, surfactant aggregations, as well as structural alterations of curcumin.