详细信息

Ni-ANIPE-enabled dynamic kinetic asymmetric addition of ketones with organoboronates    

文献类型:期刊文献

中文题名:Ni-ANIPE-enabled dynamic kinetic asymmetric addition of ketones with organoboronates

作者:Yifeng Chen[1]

机构:[1]Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering,Feringa Nobel Prize Scientist Joint Research Center,Frontiers Science Center for Materiobiology and Dynamic Chemistry,School of Chemistry and Molecular Engineering,East China University of Science and Technology,Shanghai 200237,China

年份:2023

卷号:66

期号:9

起止页码:2437

中文期刊名:Science China Chemistry

外文期刊名:中国科学(化学英文版)

收录:CSTPCD;;Scopus;CSCD:【CSCD2023_2024】;PubMed;

语种:英文

中文关键词:synthesis;tertiary;boron;

摘要:The enantioenriched tertiary alcohols are among the most privileged skeletons in pharmaceuticals,natural products and agrochemicals.Therefore,tremendous effects have been devoted to constructing this chiral moiety,which constitutes the cornerstones in modern organic synthesis.Generally,the enantioselective nucleophilic addition of ketones functionality with the organometallics reagents represents one of the most reliable strategies to forge the tertiary carbon-oxygen bond.

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