文献类型：期刊文献

英文题名：AIBN-initiated radical addition of gem-difluorinated alkyl iodides to alkynes and the Pd-catalyzed Sonogashira coupling reaction of E-phenyl difluoromethylene vinylic iodides with terminal alkynes

作者：Fang, Xiang[1];Yang, Xueyan[1];Yang, Xianjin[1,2];Mao, Shenjie[1];Wang, Zhonghua[1];Chen, Guorong[1];Wu, Fanhong[1,2]

机构：[1]E China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Lab Adv Mat, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

年份：2007

卷号：63

期号：43

起止页码：10684

外文期刊名：TETRAHEDRON

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000252092400015)，CCR-EXPANDED(收录号:WOS:000252092400015)】；

语种：英文

外文关键词：alkynes; radical addition; difluoromethylene vinylic iodides; sonogashira coupling

摘要：The addition of gem-difluorinated alkyl iodides to alkynes initiated by AIBN neatly gave the corresponding difluoromethylene vinyl iodides among which the stereoselectivity of aromatic acetylenes was high. The further coupling reaction of E-phenyl difluoromethylene vinyl iodides with terminal alkynes in the presence of catalytic palladium afforded the substituted difluorinated enynes. (C) 2007 Elsevier Ltd. All rights reserved.