文献类型：期刊文献

英文题名：A novel electrochemical sensor based on Cu@Ni/MWCNTs nanocomposite for simultaneous determination of guanine and adenine

作者：Wang, Dongyang[1];Huang, Bintong[3];Liu, Jie[3];Guo, Xia[6];Abudukeyoumu, Guzailinur[7];Zhang, Yang[2,5];Ye, Bang-Ce[1,4];Li, Yingchun[2,3]

机构：[1]Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, Shihezi 832003, Peoples R China;[2]Harbin Inst Technol, Coll Sci, Shenzhen 518055, Peoples R China;[3]Shihezi Univ, Sch Pharm, Minist Educ, Key Lab Xinjiang Phytomed Resources, Shihezi 832000, Peoples R China;[4]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[5]Harbin Inst Technol Shenzhen, Shenzhen Key Lab Organ Pollut Prevent & Control, Shenzhen, Guangdong, Peoples R China;[6]Southern Med Univ, Shenzhen Hosp, CIRC, Shenzhen 518100, Peoples R China;[7]Kashi Second Peoples Hosp, Dept Pharm, Kashi 844000, Xinjiang, Peoples R China

年份：2018

卷号：102

起止页码：389

外文期刊名：BIOSENSORS & BIOELECTRONICS

收录：;EI(收录号：20174804452917);WOS:【SCI-EXPANDED(收录号:WOS:000424176600052)】；

基金：This work is supported by National Natural Science Foundation of China (81460543, 81773680 and 21575089) and Scientific Research Foundation for Changjiang Scholars of Shihezi University (CJXZ201501).

语种：英文

外文关键词：Multi-walled carbon nanotubes; Copper nickel nanoparticles; Guanine; Adenine; Electrocatalytic oxidation; Synergistic effect

摘要：A novel electrochemical sensing platform based on combination of multi-walled carbon nanotubes and copper nickel hybrid nanoparticles (Cu@Ni/MWCNTs) was developed for simultaneous detection of guanine (G) and adenine (A). The Ni/MWCNTs and Cu@Ni/MWCNTs nanocomposites were characterized by transmission electron microscopy (TEM) and energy-dispersive X-ray spectroscopy (EDS). The electrochemical behaviors of G and A on the modified electrode were explored by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) in phosphate buffer with pH 3.0. Under the optimal conditions, electrical signals were linear over the concentration ranges from 5.0 to 180 mu M and 8.0 to 150 mu M for simultaneous determination G and A with the detection limit as low as 0.35 mu M and 0.56 mu M (S/N = 3), respectively. Furthermore, linear concentration ranges in individual determination are 1.0-180 mu M and 2.0-150 mu M with detection limits of 0.17 mu M and 0.33 mu M (S/N = 3) for G and A, respectively. The sensor was successfully used to quantify G and A in real samples. The Cu@ Ni/MWCNTs composite presented here can serve as a promising candidate for developing electrochemical sensor devices and plays an important role in widespread fields.