文献类型：期刊文献

英文题名：Pesticides have negative effects on non-target organisms

作者：Wan, Nian-Feng[1];Fu, Liwan[2];Dainese, Matteo[3];Kiaer, Lars Podenphant[4];Hu, Yue-Qing[5];Xin, Fengfei[6];Goulson, Dave[7];Woodcock, Ben A.[8];Vanbergen, Adam J.[9];Spurgeon, David J.[8];Shen, Siyuan[5];Scherber, Christoph[10,11]

机构：[1]East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai, Peoples R China;[2]Capital Med Univ, Beijing Childrens Hosp, Ctr Noncommunicable Dis Management, Natl Ctr Childrens Hlth, Beijing, Peoples R China;[3]Univ Verona, Dept Biotechnol, Verona, Italy;[4]Univ Copenhagen, Dept Plant & Environm Sci, Frederiksberg, Denmark;[5]Fudan Univ, Inst Biostat, Sch Life Sci, State Key Lab Genet Engn, Shanghai, Peoples R China;[6]Shanghai Wildlife & Protected Nat Areas Res Ctr, Shanghai 202150, Peoples R China;[7]Univ Sussex, Sch Life Sci, Brighton, England;[8]UK Ctr Ecol & Hydrol, Wallingford, England;[9]Univ Bourgogne, Univ Bourgogne Franche Comte, Inst Agro, Agroecol,INRAE, Dijon, France;[10]Leibniz Inst Anal Biodivers Change, Ctr Biodivers Monitoring & Conservat Sci, Museum Koenig, Bonn, Germany;[11]Univ Bonn, Inst Organism Biol, Bonn, Germany

年份：2025

卷号：16

期号：1

外文期刊名：NATURE COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001421591600015)】；

基金：We thank all researchers whose data and work have been included in this meta-analysis. We thank Professor Shinichi Nakagawa for providing us with constructive suggestions. N.F.W. was supported by the Shanghai Agriculture Applied Technology Development Programme, China (Grant No. 2023-02-08-00-12-F04586), Natural Science Foundation of Shanghai (22ZR1417200), National Natural Science Foundation of China (32172484), Fundamental Research Funds for the Central Universities (JKY01231718), Shanghai Science and Technology Innovation Action Plan from Shanghai Municipal Science and Technology Commission of China (22015821000) and National Ten Thousand Plan-Young Top Talents of China. L.F. was supported by the National Natural Science Foundation of China (82204063), Y.Q.H. was supported by the National Key R&D Programme of China (2023YFF1205101). D.J.S. and B.A.W. were supported by Natural Environment Research Council of UK (NE/S00135/1, NE/W005050/1, NE/S000100/1, NE/V007548/1), and C.S. was supported by the European Union's Horizon 2020 research and innovation programme under grant agreement 727284, the European Union's Horizon Europe programme under grant agreement 101081964 and the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy (EXC 2070-390732324).

语种：英文

摘要：Pesticides affect a diverse range of non-target species and may be linked to global biodiversity loss. The magnitude of this hazard remains only partially understood. We present a synthesis of pesticide (insecticide, herbicide and fungicide) impacts on multiple non-target organisms across trophic levels based on 20,212 effect sizes from 1,705 studies. For non-target plants, animals (invertebrate and vertebrates) and microorganisms (bacteria and fungi), we show negative responses of the growth, reproduction, behaviour and other physiological biomarkers within terrestrial and aquatic systems. Pesticides formulated for specific taxa negatively affected non-target groups, e.g. insecticidal neonicotinoids affecting amphibians. Negative effects were more pronounced in temperate than tropical regions but were consistent between aquatic and terrestrial environments, even after correcting for field-realistic terrestrial and environmentally relevant exposure scenarios. Our results question the sustainability of current pesticide use and support the need for enhanced risk assessments to reduce risks to biodiversity and ecosystems.