文献类型：期刊文献

英文题名：Cinchona Alkaloid Catalyzed Enantioselective Chlorination of 3-Aryloxindoles

作者：Zhao, Mei-Xin[1,2,3];Zhang, Zhi-Wang[1,2];Chen, Ming-Xiao[1,2];Tang, Wen-Hao[1,2];Shi, Min[1,2,4]

机构：[1]E China Univ Sci & Technol, Adv Mat Lab, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[2]Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China;[4]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

年份：2011

卷号：2011

期号：16

起止页码：3001

外文期刊名：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000291563200015)，CCR-EXPANDED(收录号:WOS:000291563200015)】；

基金：We are grateful for the financial support from the National Natural Science Foundation of China (20772030, 21072056) and the Fundamental Research Funds for the Central Universities, Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry.

语种：英文

外文关键词：Alkaloids; Chlorination; Enantioselectivity; Organocatalysis; Synthetic methods

摘要：O-Benzoylquinidine is an effective organocatalyst for the asymmetric chlorination of 3-aryloxindoles by using easily available N-chlorosuccinimide (NCS) as chlorine source to give the corresponding 3-aryl-3-chlorooxindoles in excellent yields and up to 93% enantiomeric excess.