文献类型：期刊文献

英文题名：Neurodynamics of up and down transitions in a single neuron

作者：Xu, Xuying[1];Wang, Rubin[1]

机构：[1]East Chine Univ Sci & Technol, Inst Cognit Neurodynam, Shanghai 200237, Peoples R China

年份：2014

卷号：8

期号：6

起止页码：509

外文期刊名：COGNITIVE NEURODYNAMICS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000344532300006)】；

语种：英文

外文关键词：Up and down transition; Bistability; Spontaneous activity; Ion channel model

摘要：Recent experimental studies have revealed that up and down transitions exist in membrane potential of neurons. This paper focuses on the neurodynamical research of these transitions in a single neuron since it is the basic to study the transitions in the neural network for further work. The results show there exists two stable levels in the neuron called up and down states. And transitions between these two states are bidirectional or unidirectional with the values of parameters changing. We also study the periodic spontaneous activity of the transitions between up and down states without any inputting stimulus which coheres with the experimental results.