文献类型：期刊文献

英文题名：A multifunctional green antibacterial rapid hemostasis composite wound dressing for wound healing

作者：Liang, Wencheng[1,2];Lu, Qiaohui[3];Yu, Fan[4];Zhang, Junyong[1];Xiao, Chuang[1];Dou, Xiaoming[2];Zhou, Yan[3];Mo, Xiumei[4];Li, Jun[5];Lang, Meidong[1]

机构：[1]East China Univ Sci & Technol, Sch Mat Sci & Engn, Shanghai Key Lab Adv Polymer Mat, Key Lab Ultrafine Mat,Minist Educ, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Ctr Photon & Biomed Diag, Sch Sci, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]East China Univ Sci & Technol, Sch Biotechnol, State Key Lab Bioreactor Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[4]Donghua Univ, Coll Chem, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China;[5]Tongji Univ, Dept Orthoped, Shanghai Peoples Hosp 10, 301 Yanchang Rd, Shanghai 200072, Peoples R China

年份：2021

卷号：9

期号：21

起止页码：7124

外文期刊名：BIOMATERIALS SCIENCE

收录：;EI(收录号：20214411107495);WOS:【SCI-EXPANDED(收录号:WOS:000700550000001)】；

基金：This research was supported by the National Key Research and Development Program (2016YFC1100703). The authors thank Research Center of Analysis and Test of East China University of Science and Technology for the help with the characterization.

语种：英文

摘要：Rapid hemostasis and antibacterial properties are essential for novel wound dressings to promote wound healing. In particular, timely and rapid hemostasis could be of benefit to reduce the mortality caused by excessive bleeding loss. Herein, we present a novel strategy of combining electrospinning technology with post-modification technology to prepare a multifunctional wound dressing, cellulose diacetate-based composite wound dressing (CDCE), with rapid hemostasis and antibacterial activity. It is interesting that the CDCE wound dressing had superhydrophilicity, high water absorption, and strong absorbing capacity, which could eliminate the exudate around the wound in a timely manner and further promote rapid hemostasis. Additionally, its excellent antibacterial properties could inhibit severe infection in the wound and accelerate wound healing. Based on these advantages, the novel CDCE wound dressing could promote wound contraction and further accelerate wound healing compared with the common traditional wound dressing gauze. Taken together, the multifunctional CDCE wound dressing has high potential for clinical application in the future.