文献类型：期刊文献

中文题名：室内灰尘中的间/对苯二甲酸单酯的可疑筛查分析

英文题名：Suspect screening analysis of isophthalate and terephthalate monoesters in indoor dust samples

作者：陈龙[1,2,3];镇华君[1,2,3,4];修光利[1,2,3,4]

机构：[1]华东理工大学资源与环境工程学院,上海200237;[2]上海市环境保护化学污染物环境标准与风险管理重点实验室,上海200237;[3]国家环境保护化工过程环境风险评价与控制重点实验室,上海200237;[4]上海污染控制与生态安全研究院,上海200092

年份：2025

卷号：47

期号：10

起止页码：64

中文期刊名：环境污染与防治

外文期刊名：Environmental Pollution & Control

收录：;北大核心:【北大核心2023】；

基金：国家自然科学基金资助项目(No.22276056);上海市浦江人才计划资助项目(No.20PJ1402700)。

语种：中文

中文关键词：高分辨质谱;可疑筛查;间苯二甲酸单酯;对苯二甲酸单酯;室内灰尘

外文关键词：high-resolution mass spectrometry;suspect screening;isophthalate monoesters;terephthalate monoesters;indoor dust

摘要：间苯二甲酸酯(IPAEs)和对苯二甲酸酯(TPAEs)作为邻苯二甲酸酯(PAEs)类塑化剂的主要替代品,其生产量及环境暴露水平逐年攀升。环境中该类物质的转化产物——间/对苯二甲酸单酯可能具有潜在生物毒性,但是它们的组成及污染特征仍不明。建立了包含54种间苯二甲酸单酯(mono-IPAEs)和101种对苯二甲酸单酯(mono-TPAEs)的化合物数据库,采用高分辨质谱技术对20份室内灰尘样品开展分析,分别识别出136个mono-IPAEs和240个mono-TPAEs的可疑物信号。结合标准品的色谱/质谱信息比对,共鉴定出6种mono-TPAEs,包括对苯二甲酸单甲酯(MMT)、对苯二甲酸单乙酯(MET)、对苯二甲酸单(2-乙基己基)酯(MEHT)、对苯二甲酸单(2-乙基-5羟基己基)酯(5OH-MEHT)、对苯二甲酸单(2-乙基-5羧基己基)酯(5CX-MEHT)和对苯二甲酸单(2-乙基-5羰基己基)酯(5OXO-MEHT)。定量分析结果表明,室内灰尘中以上6种物质的平均质量浓度分别为17 123.29、195.28、734.39、84.71、62.05、247.38 ng/g。因此,未来应对间/对苯二甲酸单酯类物质的环境风险展开进一步的调查研究。
Isophthalate esters(IPAEs)and terephthalate esters(TPAEs)have emerged as the primary substitutes for phthalate esters(PAEs)plasticizers,and their production and environmental exposure levels increase gradually.The transformation products of these substances in the environment,namely isophthalate monoesters(mono-IPAEs)and terephthalate monoesters(mono-TPAEs),may possess potential biotoxicity.However,their composition and pollution characteristics remain unclear.In this study,a compound database containing 54 mono-IPAEs and 101 mono-TPAEs was established.High-resolution mass spectrometry was employed to analyze 20 indoor dust samples,leading to the identification of suspected signals corresponding to 136 mono-IPAEs and 240 mono-TPAEs.By comparing the chromatographic and spectrometric information with standards,six mono-TPAEs were identified,including mono methyl terephthalate(MMT),mono ethyl terephthalate(MET),mono 2-(ethyl hexyl)terephthalate(MEHT),mono(2-ethyl-5-hydroxyhexyl)terephthalate(5OH-MEHT),mono(5-carboxy-2-ethylpentyl)terephthalate(5CX-MEHT),and mono(2-ethyl-5-oxohexyl)terephthalate(5OXO-MEHT).Quantitative analysis revealed the average concentrations of these six substances in indoor dust was 17123.29,195.28,734.39,84.71,62.05 and 247.38 ng/g,respectively.Therefore,further investigation into the environmental risks associated with mono-IPAEs and mono-TPAEs was warranted.