文献类型：期刊文献

英文题名：Facile Synthesis of Monodisperse Superparamagnetic Fe3O4 Core@hybrid@Au Shell Nanocomposite for Bimodal Imaging and Photothermal Therapy

作者：Dong, Wenjie[1];Li, Yongsheng[1];Niu, Dechao[1];Ma, Zhi[2];Gu, Jinlou[1];Chen, Yi[3];Zhao, Wenru[1];Liu, Xiaohang[4];Liu, Changsheng[1];Shi, Jianlin[1,5]

机构：[1]E China Univ Sci & Technol, Sch Mat Sci & Engn, Key Lab Ultrafine Mat, Minist Educ, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China;[4]Fudan Univ, Dept Radiol, Shanghai Canc Ctr, Shanghai 200032, Peoples R China;[5]Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China

年份：2011

卷号：23

期号：45

起止页码：5392

外文期刊名：ADVANCED MATERIALS

收录：;EI(收录号：20114914575835);WOS:【SCI-EXPANDED(收录号:WOS:000297457700010)】；

基金：This work was financially supported by the National Basic Research Program of China (973 Program, 2012CB933602); Program for New Century Excellent Talents in University (NCET-10-0379); Scientific Innovation Project of Shanghai Municipal Education Commission (Grant No. 11ZZ53); and the National Natural Science Foundation of China (Grant Nos. 51172070, 51132009), Program for Changjiang Scholars and Innovative Research Team in University (IRT0825).

语种：英文

外文关键词：gold nanoshells; superparamagnetic materials; photothermal therapy; magnetic resonance imaging

摘要：A simple seed-mediated growth route is developed to fabricate monodisperse, uniform superparamagnetic Fe3O4 core/gold shell structured nanocomposites with tunable sizes and optical properties, in which gold seed formation and attachment onto the core surface via S-Au covalent bonding proceeds almost simultaneously in the one-pot synthesis. The as-prepared nanocomposite is demonstrated to have a great potential for magnetic resonance imaging (MRI)-guided, focused photothermal tumor therapy under near-IR laser radiation.