文献类型：期刊文献

英文题名：Synthesis and Antibacterial Performance of Functional Organic-Inorganic Silica Nanocomposites Based on Novel Zwitterionic Polymer

作者：Sun, Yunlong[1];Chen, Changlin[1];Xu, Heng[3];Xu, Guanzhe[1];Zhao, Li[2];Lang, Meidong[1]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab Adv Polymer Mat, Key Lab Ultrafine Mat, Minist Educ,Sch Mat Sci & Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, New World Inst Biotechnol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[3]Collaborat Innovat Ctr Petrochem New Mat, Anqing 246011, Anhui, Peoples R China

年份：2017

卷号：27

期号：5

起止页码：1351

外文期刊名：JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS

收录：;EI(收录号：20172203719146);WOS:【SCI-EXPANDED(收录号:WOS:000407944900023)】；

基金：This research was supported by National Key Technology Support Program (No. 2015BAD16B05-04), the National Natural Science Foundation of China (No. 21274039), Specialized Research Fund for the Doctoral Program of Higher Education (No. 20130074110007) and Natural Science Foundation of Shanghai (No. 2013ZR1412100).

语种：英文

外文关键词：Silica nanocomposites; 4-Vinyl pyridine; Zwitterionic polymer; Cationic polymer; Antibacterial ability

摘要：Nano-sized silica particles (SiO2 NPs) of 30 +/- 5 nm were modified by the coupling agent of triethoxyvinylsilane and polymer 4-vinyl pyridine (P4VP) was "grafted" onto the surface of modified SiO2 NPs by adopting the "grafting from" way. Then, the P4VP brush of SiO2 NPs was quaternized by ethyl bromoacetate, iodoethane, 3-bromopropionic acid and 1,3-propanesulfonate to obtain four water-insoluble, functional and novel organic-inorganic silica nanocomposites (SiO2/P4VP-eb, SiO2/P4VP-ie, SiO2/P4VP-bpa and SiO2/P4VP-psl), respectively. The antibacterial performance of four functional silica nanocomposites above was investigated by using Escherichia coli ATTC25922 as model bacterium via the colony count method. When the sterilizing ratios of SiO2/P4VP-psl, SiO2/P4VP-bpa, SiO2/P4VP-eb and SiO2/P4VP-ie against E. coli with bacterium age of 4 h (OD600 nm = 2.5) reached 100%, the critical concentration value was 3, 5, 12 and 11 mg/mL, respectively. The results showed that although four functional silica nanocomposites all possessed excellent antibacterial ability, zwitterionic silica nanocomposites (SiO2/P4VP-psl, SiO2/P4VP-bpa) possessed stronger antibacterial ability than cationic silica nanocomposites (SiO2/P4VP-eb, SiO2/P4VP-ie).