文献类型：期刊文献

英文题名：Generation of MnO2 nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione

作者：Yang, Qingsong[1];Li, Li[1];Zhao, Fang[1];Wang, Yunwei[1];Ye, Zhishuang[1];Guo, Xuhong[1,2]

机构：[1]East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[2]Shihezi Univ, Engn Res Ctr Mat Chem Engn Xinjiang Bingtuan, Xinjiang 832000, Peoples R China

年份：2019

卷号：248

起止页码：89

外文期刊名：MATERIALS LETTERS

收录：;EI(收录号：20191406738136);WOS:【SCI-EXPANDED(收录号:WOS:000466352900023)】；

基金：We gratefully thank the financial support from the NSFC Grants (51761135128 and 51773061), and Key Scientific and Technological Project of Xinjiang Bingtuan (2018AB025). We also thank Shanghai Synchrotron Radiation Facility for experimental support.

语种：英文

外文关键词：Polymers; Nanocomposites; Spherical polyelectrolyte brush; Nanozyme; MnO2 nanosheets; SAXS

摘要：Novel MnO2 nanozymes were prepared as nanosheets in situ using spherical poly[(2-methacryloyloxyethyl) trimethyl ammonium chloride] (PDMC) brushes (SPB) as nanoreactors. The prepared MnO2 nanozymes were immobilized in SPB (SPB-MnO2) showing high stability and excellent oxidase-like property which could oxidize 3,30,5,50-tetramethylbenzidine (TMB) into oxidized TMB (oxTMB), accompanied by the change of absorption at 653 nm. The MnO2 nanosheets could be decomposed by trace amount of glutathione (GSH) under acidic environment as validated by small angle X-ray scattering (SAXS). The SPB-MnO2/TMB system, with a detection limit of 450 nM, should be an ideal candidate for colorimetric detection of GSH. This work opens a new way to prepare highly stable nanozymes for the detection of GSH. (C) 2019 Published by Elsevier B.V.