文献类型：期刊文献

英文题名：Preparation of novel β-cyclodextrin chiral stationary phase based on click chemistry

作者：Zhang, Yongping[1];Guo, Zhimou[3];Ye, Jinxing[1];Xu, Qing[3];Liang, Xinmiao[1,3];Lei, Aiwen[2]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China;[3]Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

年份：2008

卷号：1191

期号：1-2

起止页码：188

外文期刊名：JOURNAL OF CHROMATOGRAPHY A

收录：;EI(收录号：20081911248389);WOS:【SCI-EXPANDED(收录号:WOS:000256326400021)】；

语种：英文

外文关键词：beta-cyclodextrin; chiral stationary phases; click chemistry; chiral separation

摘要：A facile strategy based on click chemistry for preparation of the structurally well-defined native beta-cyclodextrin (beta-CD) based chiral stationary phase (CSP) was proposed. The beta-CD CSP was evaluated by enatioseparation of benzoin, trans-stilbene oxide, Troger's base, bendroflumethiazide, ketoprofen, chlorthalidone, three flavanone compounds and two beta-adrenergic blocking agents under reversed phase high performance liquid chromatography. The chromatographic results demonstrate the chiral separation ability of click beta-CD CSP and illustrate the usefulness of click chemistry in the preparation of beta-CD based CSP. (c) 2007 Elsevier B.V. All rights reserved.