文献类型：期刊文献

英文题名：Unveiling the Intrinsic Catalytic Activities of Single-Gold-Nanoparticle-Based Enzyme Mimetics

作者：Hafez, Mahmoud Elsayed[1];Ma, Hui[1];Ma, Wei[1];Long, Yi-Tao[1]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2019

卷号：58

期号：19

起止页码：6327

外文期刊名：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

收录：;EI(收录号：20191406729163);WOS:【SCI-EXPANDED(收录号:WOS:000471976400032)】；

基金：This research was supported by the National Natural Science Foundation of China (21775043, 214210047), the Program of Introducing Talents of Discipline to Universities (B16017), Innovation Program of Shanghai Municipal Education Commission (2017-01-07-00-02-E00023), and the Fundamental Research Funds for the Central Universities (222201718001, 222201717003).

语种：英文

外文关键词：electrocatalysis; enzyme mimetics; gold nanoparticle; nanocatalysis; nanozyme

摘要：Gold nanoparticles (AuNPs) have been demonstrated to serve as effective nanomaterial-based enzyme mimetics (nanozymes) for a number of enzymatic reactions under mild conditions. The intrinsic glucose oxidase and peroxidase activities of single AuNPs and Ag-Au nanohybrids, respectively, were investigated by single NP collision electrochemical measurements. A significantly high turnover number of nanozymes was obtained from individual catalytic events compared with the results from the classical, ensemble-averaged measurements. The unusual enhancement of catalytic activity of single nanozymes is believed to originate from the high accessible surface area of monodispersed NPs and the high activities of carbon-supported NPs during single-particle collision at a carbon ultramicroelectrode. This work introduces a new method for the precise characterization of the intrinsic catalytic activities of nanozymes, giving further insights to the design of high-efficiency nanomaterial catalysts.