文献类型：期刊文献

英文题名：Tumor-cell targeting polydiacetylene micelles encapsulated with an antitumor drug for the treatment of ovarian cancer

作者：Yao, Defan;Li, Shang;Zhu, Xiaomin;Wu, Junchen[1];Tian, He

机构：[1]East China Univ Sci & Technol, Key Labs Adv Mat, Shanghai 200237, Peoples R China; East China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2017

卷号：53

期号：7

起止页码：1233

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000394244000004)】；

基金：We thank the National Basic Research 973 Program (2013CB733700), and NSFC/China (91529101 and 21572057) for financial support.

语种：英文

摘要：Peptide functionalized polydiacetylene (PDA) micelles encapsulated with camptothecin (CPT) kill ovarian cancer cells by the lysosome release of anticancer drug CPT. Moreover, the sub-30 nm PDA micelles penetrate efficiently into a tumor for enhanced therapeutic efficacy.