文献类型：期刊文献

英文题名：Stable water-soluble quantum dots capped by poly(ethylene glycol) modified dithiocarbamate

作者：Li, Yan[1];Shen, Bing[1];Liu, Lu[1];Xu, Hu[1];Zhong, Xinhua[1]

机构：[1]E China Univ Sci & Technol, Inst Appl Chem, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China

年份：2012

卷号：410

起止页码：144

外文期刊名：COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

收录：;EI(收录号：20123115301652);WOS:【SCI-EXPANDED(收录号:WOS:000307797900020)】；

基金：We thank Chenguang Program of the Shanghai Education Commission (11CG31), the National Natural Science Foundation of China (No. 21175043), the Science and Technology Commission of Shanghai Municipality (11JC1403100), the Fujian Provincial Key Laboratory of Nanomaterials (NM10-06), and the Fundamental Research Funds for the Central Universities, and for financial supports.

语种：英文

外文关键词：PEG; Dithiocarbamate; Iminodiacetic acid; QDs; Water-soluble

摘要：A new bifunctional ligand (IA-PEG-DTC), poly(ethylene glycol) (PEG) appended dithiocarbamate derived from iminodiacetic acid, has been designed and synthesized. The obtained IA-PEG-DTC ligand with the dithiocarbamate group strongly bonding to the surface atom of quantum dots (QDs), the PEG segment rendering QDs water-soluble, and the free carboxylic group available for further bioconjugation was used successfully to transfer initial oil-soluble QDs into water-soluble ones. The resulting IA-PEG-DTC capped water-soluble QDs have relatively small hydrodynamic size, and importantly, retain high fluorescence quantum yield of the original hydrophobic QDs. In addition, the obtained water-soluble QDs exhibit excellent colloidal stability under conditions of wide pH range (2-13), long-term UV-irradiation, the boiling state, and high salt concentrations. These results indicate that the water-soluble QDs coated by the bifunctional IA-PEG-DTC ligand have potential for applications in cellular imaging and biosensor. (C) 2012 Elsevier B.V. All rights reserved.