文献类型：期刊文献

英文题名：A polar stationary phase obtained by surface-initiated polymerization of hyperbranched polyglycerol onto silica

作者：Geng, Huiliang[1];Jing, Jie[1];Zhang, Feifang[1];Zhang, Feng[2];Yang, Bingcheng[1]

机构：[1]East China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Shanghai 200237, Peoples R China;[2]Chinese Acad Inspect & Quarantine, Inst Food Safety, Beijing 100176, Peoples R China

年份：2020

卷号：209

外文期刊名：TALANTA

收录：;EI(收录号：20194807740331);WOS:【SCI-EXPANDED(收录号:WOS:000509632900042)】；

基金：This work was sponsored by the National Key Research and Development Program of China (2018YFC1603500) and National Natural Science Foundation of China (No. 21874044).

语种：英文

外文关键词：Hydrophilic interaction liquid chromatography; Stationary phase; Surface-initiated polymerization; Hyperbranched polyglycerol

摘要：A novel polar stationary phase for hydrophilic interaction chromatography (HILIC) is prepared by surface-initiated polymerization of hyperbranched polyglycerol onto silica. Such polymerization offers an easy way to tune the cabon load. The stationary phase showed obvious hydrogen bonding interaction and typical HILIC character, exhibiting nealy-universal separation ability towards polar analytes. Good peak shape and high separation efficiency was observed for model polar analytes, including nucleosides and nucleic bases, aromatic acids, organic bases, vitamins, saccharides, amino acids, e.g. 35,000-58,000 plate counts per meter for five water-soluble vitamins.