文献类型：期刊文献

英文题名：Motorized Macrocycle: A Photo-responsive Host with Switchable and Stereoselective Guest Recognition

作者：Liu, Yue[1,2];Zhang, Qi[1,2,3,4];Crespi, Stefano[3,4];Chen, Shaoyu[1,2,3,4];Zhang, Xiu-Kang[1,2];Xu, Tian-Yi[1,2];Ma, Chang-Shun[1,2];Zhou, Shang-Wu[1,2];Shi, Zhao-Tao[1,2];Tian, He[1,2];Feringa, Ben L.[1,2,3,4];Qu, Da-Hui[1,2]

机构：[1]East China Univ Sci & Technol, Frontiers Sci Ctr Mat Biol & Dynam Chem, Feringa Nobel Prize Scientist Joint Res Ctr, Inst Fine Chem,Sch Chem & Mol Engn,Key Lab Adv Ma, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Frontiers Sci Ctr Mat Biol & Dynam Chem, Feringa Nobel Prize Scientist Joint Res Ctr, Inst Fine Chem,Sch Chem & Mol Engn,Joint Int Res, Shanghai 200237, Peoples R China;[3]Univ Groningen, Stratingh Inst Chem, Ctr Syst Chem, Nijenborgh 4, NL-9747 AG Groningen, Netherlands;[4]Univ Groningen, Zernike Inst Adv Mat, Nijenborgh 4, NL-9747 AG Groningen, Netherlands

年份：2021

卷号：60

期号：29

起止页码：16129

外文期刊名：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

收录：;EI(收录号：20212510519669);WOS:【SCI-EXPANDED(收录号:WOS:000661671300001)】；

基金：This work was supported by the National Natural Science Foundation of China (grants 22025503, 21790361, 21871084, and 21672060), Shanghai Municipal Science and Technology Major Project (grant 2018SHZDZX03), the Fundamental Research Funds for the Central Universities, the Programme of Introducing Talents of Discipline to Universities (grant B16017), Program of Shanghai Academic/Technology Research Leader (19XD1421100), the Shanghai Science and Technology Committee (grant 17520750100). This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skodowska Curie grant agreement (Q. Zhang: individual fellowship No. 101025041; S. Crespi: individual fellowship No. 838280). B.L.F. acknowledges financial support from the European Research Council (ERC; advanced grant No.694345 to B.L.F.) and the Dutch Ministry of Education, Culture and Science (Gravitation program No.024.001.035). We thank the Research Center of Analysis and Test of East China University of Science and Technology for help on the characterization.

语种：英文

外文关键词：capture and release; host-guest interactions; motorized macrocycles; photo-responsiveness; stereoselectivity

摘要：Designing photo-responsive host-guest systems can provide versatile supramolecular tools for constructing smart systems and materials. We designed photo-responsive macrocyclic hosts, modulated by light-driven molecular rotary motors enabling switchable chiral guest recognition. The intramolecular cyclization of the two arms of a first-generation molecular motor with flexible oligoethylene glycol chains of different lengths resulted in crown-ether-like macrocycles with intrinsic motor function. The octaethylene glycol linkage enables the successful unidirectional rotation of molecular motors, simultaneously allowing the 1:1 host-guest interaction with ammonium salt guests. The binding affinity and stereoselectivity of the motorized macrocycle can be reversibly modulated, owing to the multi-state light-driven switching of geometry and helicity of the molecular motors. This approach provides an attractive strategy to construct stimuli-responsive host-guest systems and dynamic materials.