文献类型：期刊文献

英文题名：Rational Screening of Deep Eutectic Solvents for the Direct Extraction of α-Tocopherol from Deodorized Distillates

作者：Cheng, Jie[1];Qin, Hao[2];Cheng, Hongye[1];Song, Zhen[1];Qi, Zhiwen[1];Sundmacher, Kai[2,3]

机构：[1]East China Univ Sci & Technol, Sch Chem Engn, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[2]Max Planck Inst Dynam Complex Tech Syst, Proc Syst Engn, D-39106 Magdeburg, Germany;[3]Otto von Guericke Univ, Proc Syst Engn, D-39106 Magdeburg, Germany

年份：2022

卷号：10

期号：25

起止页码：8216

外文期刊名：ACS SUSTAINABLE CHEMISTRY & ENGINEERING

收录：;EI(收录号：20223012419922);WOS:【SCI-EXPANDED(收录号:WOS:000820443100001)】；

基金：This research is supported by the Deutsche Forschungsgemeinschaft (DFG) and the National Natural Science Foundation of China (NSFC) under the grants SU 189/9-1 and 21861132019, respectively. The Natural Science Foundation of Shanghai (19ZR1412600) is also acknowledged.

语种：英文

外文关键词：deep eutectic solvent screening; alpha-tocopherol extraction; COSMO-RS; extraction potential estimation; solid-liquid equilibria prediction; phase splitting check; EHS impact assessment; experimental validation

摘要：As traditional methods for retrieving natural vitamin E suffer from harsh operating conditions and poor process performance, seeking more energy-efficient and sustainable alternative approaches is highly desirable. In this work, deep eutectic solvents (DESs) as a class of emerging media are particularly proposed for the extraction of vitamin E (modeled by alpha-tocopherol) from deodorized distillates under mild operating conditions. To select DESs suitable for this task, a rational screening method is presented which covers the thermodynamic evaluation of individual components and component combinations, the assessment of environment, health, and safety (EHS) impacts of components, and the eutectic behavior estimation of component combinations. Based on experimentally reported DESs from the literature, individual components as well as random combinations of potential hydrogen bond acceptors (HBAs) and hydrogen bond donors (HBDs) are successively prescreened by COSMO-RS predicted thermodynamic proper-ties. Five EHS-related properties of HBDs are assessed by VEGA. The formation of eutectics and the corresponding operating window of different HBA-HBD combinations are estimated by COSMO-RS solid-liquid equilibria prediction. Experiments are finally performed with the top-ranked DESs, which well validates the reliability of the screening method and identifies tetrabutylphosphonium chloride-ethanolamine (2:1) as a suitable DES for the alpha-tocopherol extraction.